Jika Bagnaia tampil dengan performa konsisten, maka kecil kemungkinan Quartararo dapat mempertahankan gelar juaranya.
Hasil FP2 MotoGP Valencia 2022:
1. Luca Marini, Mooney VR46 Ducati (GP22) 1'30.217s
2. Jorge Martin, Pramac Ducati (GP22) +0.105s
3. Jack Miller, Ducati Lenovo (GP22) +0.128s
4. Marc Marquez, Repsol Honda (RC213V) +0.173s
5. Enea Bastianini, Gresini Ducati (GP21) +0.177s
6. Miguel Oliveira, Red Bull KTM (RC16) +0.205s
7. Johann Zarco, Pramac Ducati (GP22) +0.207s
8. Fabio Quartararo, Monster Yamaha (YZR-M1) +0.225s
9. Francesco Bagnaia, Ducati Lenovo (GP22) +0.230s
10. Brad Binder, Red Bull KTM (RC16) +0.302s
11. Alex Rins, Suzuki Ecstar (GSX-RR) +0.490s
12. Maverick Viñales, Aprilia Racing (RS-GP) +0.597s
13. Aleix Espargaro, Aprilia Racing (RS-GP) +0.673s
14. Joan Mir, Suzuki Ecstar (GSX-RR) +0.787s